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Evacuation and Shelter-in-Place Training > Extremely Hazardous Substance (EHS) Facility Managers
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Five Hazardous Characteristics:

(1) Acute (Immediate) Health Hazard: Includes corrosive, highly toxic, irritant, sensitizer, toxic, and other hazardous chemicals which cause an adverse effect to a target organ (as defined under 1910.1200 of Title 29 of the Code of Federal Regulations) and manifests itself within a short period of time following a one-time, high exposure to the substance.

"Corrosive" means a chemical that causes visible destruction of, or irreversible alterations in, living tissue by chemical action at the site of contact.

"Highly toxic" means a chemical falling within any of the following categories:

"Irritant" means a chemical which causes a reversible inflammation at the site of contact.

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